Graduate School of Agricultural and Life Sciences, The University of Tokyo
Bunpei SATO
MiZ Co., Ltd.
Shota USHIAMA
Graduate School of Agricultural and Life Sciences, The University of Tokyo
Shinji OKADA
Graduate School of Agricultural and Life Sciences, The University of Tokyo
Keiko ABE
Graduate School of Agricultural and Life Sciences, The University of Tokyo Food Safety and Reliability Project, Kanagawa Academy of Science and Technology
Soichi ARAI
Food Safety and Reliability Project, Kanagawa Academy of Science and Technology Department of Nutritional Science, Faculty of Applied Bioscience, Tokyo University of Agriculture
Published: April 23, 2011Received: November 19, 2010Available on J-STAGE: -Accepted: December 27, 2010
Advance online publication: April 22, 2011
Revised: -
The effects of the administration of molecular hydrogen-saturated drinking water (hydrogen water) on hepatic gene expression were investigated in rats. Using DNA microarrays, 548 upregulated and 695 downregulated genes were detected in the liver after 4 weeks of administration of hydrogen water. Gene Ontology analysis revealed that genes for oxidoreduction-related proteins, including hydroxymethylglutaryl CoA reductase, were significantly enriched in the upregulated genes.
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