Effects of a Plum (Prunus mume Siebold and Zucc.) Ethanol Extract on the Immune System in Vivo and in Vitro

Ryohei TSUJI; Hideki KOIZUMI; Daisuke FUJIWARA

doi:10.1271/bbb.100886

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Effects of a Plum (Prunus mume Siebold and Zucc.) Ethanol Extract on the Immune System in Vivo and in Vitro

Ryohei TSUJI, Hideki KOIZUMI, Daisuke FUJIWARA

著者情報

キーワード: plum ethanol extract, innate immunity, immune enhancement, interleukin-12, ripeness

ジャーナルフリー早期公開

論文ID: 100886

DOI https://doi.org/10.1271/bbb.100886

この記事には本公開記事があります。

The final version of this article is now available: Vol. 75 (2011) , No. 10 p.2011

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抄録

The effect of a plum ethanol extract (PEE) on immunity was analyzed. An oral administration of PEE increased the interleukin (IL)-12p40 concentration in the serum and T-cell ratio in the spleen. In vitro studies revealed that PEE stimulated IL-12p70 production in peritoneal macrophages and natural killer activity. These findings suggest that PEE enhanced the immune function by stimulating innate immune cells.

責任著者(Corresponding author)

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