Department of Applied Biological Chemistry, Graduate School of Agricultural and Life Sciences, The University of Tokyo
Takanobu SAKURAI
Department of Applied Biological Chemistry, Graduate School of Agricultural and Life Sciences, The University of Tokyo General Research Institute of Food Science and Technology, Nissin Foods Holdings Co., Ltd.
Shinji OKADA
Department of Applied Biological Chemistry, Graduate School of Agricultural and Life Sciences, The University of Tokyo
Keiko ABE
Department of Applied Biological Chemistry, Graduate School of Agricultural and Life Sciences, The University of Tokyo Kanagawa Academy of Science and Technology
Takumi MISAKA
Department of Applied Biological Chemistry, Graduate School of Agricultural and Life Sciences, The University of Tokyo
The strong bitter peptide, Phe-Phe-Pro-Arg, activated cultured cells expressing either of the known human bitter taste receptors, hTAS2R8 and hTAS2R39. The partial structure of Pro-Arg activated hTAS2R39, but did not activate hTAS2R8. These receptors may not indiscriminately recognize bitter peptides, but have a differential function in their recognition.
