Aspergillus oryzae laeA Regulates Kojic Acid Synthesis Genes

Ken ODA; Akiko KOBAYASHI; Shinichi OHASHI; Motoaki SANO

doi:10.1271/bbb.110235

This article has now been updated. Please use the final version.

Aspergillus oryzae laeA Regulates Kojic Acid Synthesis Genes

Ken ODA, Akiko KOBAYASHI, Shinichi OHASHI, Motoaki SANO

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Keywords: Aspergillus oryzae, LaeA, kojic acid

JOURNAL FREE ACCESS Advance online publication

Article ID: 110235

DOI https://doi.org/10.1271/bbb.110235

The final version of this article is now available: Vol. 75 (2011) , No. 9 p.1832

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Abstract

Kojic acid synthesis genes regulation was investigated in Aspergillus oryzae. Our results indicate that kojic acid production was lost in the laeA disruption strain, but was recovered in the LaeA complement strain. Real-time PCR also confirmed that expression of kojic acid biosynthesis genes decreased in the laeA disruption strain, indicating that these genes are under the control of LaeA.

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