Ingested Maple Syrup Evokes a Possible Liver-Protecting Effect—Physiologic and Genomic Investigations with Rats

Yuki WATANABE; Asuka KAMEI; Fumika SHINOZAKI; Tomoko ISHIJIMA; Kota IIDA; Yuji NAKAI; Soichi ARAI; Keiko ABE

doi:10.1271/bbb.110532

This article has now been updated. Please use the final version.

Ingested Maple Syrup Evokes a Possible Liver-Protecting Effect—Physiologic and Genomic Investigations with Rats

Yuki WATANABE, Asuka KAMEI, Fumika SHINOZAKI, Tomoko ISHIJIMA, Kota IIDA, Yuji NAKAI, Soichi ARAI, Keiko ABE

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Keywords: maple syrup, DNA microarray, liver, ammonia, amino acid metabolism

JOURNAL FREE ACCESS Advance online publication

Article ID: 110532

DOI https://doi.org/10.1271/bbb.110532

The final version of this article is now available: Vol. 75 (2011) , No. 12 p.2408

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Abstract

Rats fed a 20%-maple syrup diet (maple syrup group) for 11 d showed significantly lower values of the hepatic function markers than those fed a 20%-sugar mix syrup diet (control). The reason was suggested by a DNA microarray analysis which revealed that the expression of genes for the enzymes of ammonia formation were down-regulated in the liver of the maple syrup group.

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