Improvement in the High-Fat Diet-Induced Dyslipidemia and Adiponectin Levels by Fish Oil Feeding Combined with Food Restriction in Obese KKAy Mice

Masaki WAKUTSU; Nobuyo TSUNODA; Yasuki MOCHI; Mitsuki NUMAJIRI; Sachiko SHIBA; Etsuko MURAKI; Keizo KASONO

doi:10.1271/bbb.110743

This article has now been updated. Please use the final version.

Improvement in the High-Fat Diet-Induced Dyslipidemia and Adiponectin Levels by Fish Oil Feeding Combined with Food Restriction in Obese KKAy Mice

Masaki WAKUTSU, Nobuyo TSUNODA, Yasuki MOCHI, Mitsuki NUMAJIRI, Sachiko SHIBA, Etsuko MURAKI, Keizo KASONO

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Keywords: fish oil, food restriction, weight reduction, dyslipidemia, adiponectin

JOURNAL FREE ACCESS Advance online publication

Article ID: 110743

DOI https://doi.org/10.1271/bbb.110743

The final version of this article is now available: Vol. 76 (2012) , No. 5 p.1011

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Abstract

The effect on weight reduction of fish oil combined with food restriction in comparison with that of beef tallow was investigated in high-fat diet-induced obese KKAy mice. Although the reduction of body and white adipose tissue weight was similar in the two groups, fish oil increased adiponectin levels in the plasma, improved dyslipidemia accompanied by suppression of lipid synthesis in the liver when compared with beef tallow.

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