Oxidative Stress during Development of Alcoholic Fatty Liver: Therapeutic Potential of Cacao Polyphenol

Koichiro SUZUKI; Kiyotaka NAKAGAWA; Taiki MIYAZAWA; Shunji KATO; Fumiko KIMURA; Masanori KAMEI; Teruo MIYAZAWA

doi:10.1271/bbb.130380

This article has now been updated. Please use the final version.

Oxidative Stress during Development of Alcoholic Fatty Liver: Therapeutic Potential of Cacao Polyphenol

Koichiro SUZUKI, Kiyotaka NAKAGAWA, Taiki MIYAZAWA, Shunji KATO, Fumiko KIMURA, Masanori KAMEI, Teruo MIYAZAWA

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Keywords: alcoholic fatty liver, lipid peroxide, tocopherol, cacao polyphenol, triglyceride

JOURNAL FREE ACCESS Advance online publication

Article ID: 130380

DOI https://doi.org/10.1271/bbb.130380

The final version of this article is now available: Vol. 77 (2013), No. 8 pp. 1792-1794

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Abstract

The lipid and antioxidative/oxidative profiles of livers from rats fed an ethanol liquid diet for 8 weeks provided evidence for an involvement of oxidative stress (e.g., phospholipid peroxidation) in the development of alcoholic fatty liver (AFL), possibly in an early stage. Cacao polyphenol supplementation produced an ameliorating effect, and may help in AFL prevention.

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