Alleviation of Weight-Gain in Mice by an Ethanolic Extract from Rubus coreanus under Conditions of a High-Fat Diet and Exercise

Changsik CHUNG; Yanghee YOU; Ho-Geun YOON; Kyungmi KIM; Yoo-Hyun LEE; Jeongmin LEE; Jin Woong CHUNG; Hyunjung CHUNG; Soojin YANG; Woojin JUN

doi:10.1271/bbb.130443

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Alleviation of Weight-Gain in Mice by an Ethanolic Extract from Rubus coreanus under Conditions of a High-Fat Diet and Exercise

Changsik CHUNG, Yanghee YOU, Ho-Geun YOON, Kyungmi KIM, Yoo-Hyun LEE, Jeongmin LEE, Jin Woong CHUNG, Hyunjung CHUNG, Soojin YANG, Woojin JUN

著者情報

キーワード: Rubus coreanus, anti-obesity, weight gain, exercise, antioxidant

ジャーナルフリー早期公開

論文ID: 130443

DOI https://doi.org/10.1271/bbb.130443

この記事には本公開記事があります。

The final version of this article is now available: Vol. 77 (2013) , No. 10 p.2148-2150

詳細

抄録

The administration of an ethanolic extract (RCE) from Rubus coreanus significantly reduced the body weight and epididymal fat tissue of mice under conditions of a high-fat diet (HFD) and exercise. The mice also displayed enhanced muscular carnitine palmitoyltransferase 1 (CPT1) expression and increased superoxide dismutase and glutathione levels. These results suggest that RCE exerted an anti-obesity effect by up-regulating CPT1 and elevating the level of antioxidants.

責任著者(Corresponding author)

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