Identification of a Peptide Mimic of Bioactive Gibberellins with Affinity to GA 2-Oxidase

Haruko Sekimoto; Seung-Hyun Park; Masatoshi Nakajima; Isomaro Yamaguchi; Yoshihito Suzuki

doi:10.1271/bbb.60141

This article has now been updated. Please use the final version.

Identification of a Peptide Mimic of Bioactive Gibberellins with Affinity to GA 2-Oxidase

Haruko Sekimoto ^†, Seung-Hyun Park, Masatoshi Nakajima ^†, Isomaro Yamaguchi ^†, Yoshihito Suzuki ^†

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Keywords: random peptide library, peptide mimic, gibberellin, GA 2-oxidase

JOURNAL FREE ACCESS Advance online publication

Article ID: 60141

DOI https://doi.org/10.1271/bbb.60141

The final version of this article is now available: Vol. 70 (2006) , No. 8 p.2004

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Abstract

Previously we reported the first example of peptide mimics of a small hydrophobic molecule, a phytohormone gibberellin. The second peptide mimic of gibberellin has been identified from random peptide libraries by its affinity to a type of catalyzing enzyme of gibberellins, which specifically recognizes bioactive gibberellins. These results suggest that even hydrophobic compounds can be mimicked by peptides.

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