Dietary Supplementation with Epigallocatechin Gallate Elevates Levels of Circulating Adiponectin in Non-Obese Type-2 Diabetic Goto-Kakizaki Rats

Masaya SHIMADA; Kazuki MOCHIZUKI; Naoko SAKURAI; Toshinao GODA

doi:10.1271/bbb.70174

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Dietary Supplementation with Epigallocatechin Gallate Elevates Levels of Circulating Adiponectin in Non-Obese Type-2 Diabetic Goto-Kakizaki Rats

Masaya SHIMADA, Kazuki MOCHIZUKI, Naoko SAKURAI, Toshinao GODA

著者情報

キーワード: adiponectin, epigallocatechin gallate (EGCG), Goto-Kakizaki (GK) rats, insulin secretory dysfunction

ジャーナルフリー早期公開

論文ID: 70174

DOI https://doi.org/10.1271/bbb.70174

この記事には本公開記事があります。

The final version of this article is now available: Vol. 71 (2007) , No. 8 p.2079

詳細

抄録

Epigallocatechin gallate (EGCG) reportedly enhances plasma adiponectin levels in models of insulin resistance and obesity. In this study, we found that EGCG increases plasma adiponectin levels and decreases plasma triacylglycerol levels in non-obese diabetic Goto-Kakizaki rats with insulin secretory dysfunction. These results suggest that EGCG ameliorates lipid metabolic abnormality even in non-obese rats, probably by increasing adiponectin production.

責任著者(Corresponding author)

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