Effect of Vaccinium ashei reade Leaves on Angiotensin Converting Enzyme Activity in Vitro and on Systolic Blood Pressure of Spontaneously Hypertensive Rats in Vivo

Hiroshi SAKAIDA; Koji NAGAO; Kouki HIGA; Bungo SHIROUCHI; Nao INOUE; Fumie HIDAKA; Takanori KAI; Teruyoshi YANAGITA

doi:10.1271/bbb.70277

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Effect of Vaccinium ashei reade Leaves on Angiotensin Converting Enzyme Activity in Vitro and on Systolic Blood Pressure of Spontaneously Hypertensive Rats in Vivo

Hiroshi SAKAIDA, Koji NAGAO, Kouki HIGA, Bungo SHIROUCHI, Nao INOUE, Fumie HIDAKA, Takanori KAI, Teruyoshi YANAGITA

著者情報

キーワード: Vaccinium ashei reade, blueberry leaf, angiotensin converting enzyme, spontaneously hypertensive rat

ジャーナルフリー早期公開

論文ID: 70277

DOI https://doi.org/10.1271/bbb.70277

この記事には本公開記事があります。

The final version of this article is now available: Vol. 71 (2007) , No. 9 p.2335

詳細

抄録

The hypotensive effects of Vaccinium ashei reade (blueberry) leaves were studied in vitro and in vivo. Blueberry leaf showed a strong inhibitory effect on angiotensin-converting enzyme activity in vitro. Additionally, feeding of blueberry leaf suppressed the development of essential hypertension in spontaneously hypertensive rats in vivo. These results promise the use of blueberry leaf as a source of dietary hypotensive components.

責任著者(Corresponding author)

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