The Occurrence of HR1b in the Venom of the Snake Okinawa Habu (Protobothrops flavoviridis)

Nobuya MORINE; Seiko MATSUDA; Koki TERADA; Hironori IWASAKI; Hirosuke OKU

doi:10.1271/bbb.70540

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The Occurrence of HR1b in the Venom of the Snake Okinawa Habu (Protobothrops flavoviridis)

Nobuya MORINE, Seiko MATSUDA, Koki TERADA, Hironori IWASAKI, Hirosuke OKU

著者情報

キーワード: hemorrhagic metalloproteinase, HR1b, Protobothrops flavoviridis, Okinawa habu

ジャーナルフリー早期公開

論文ID: 70540

DOI https://doi.org/10.1271/bbb.70540

この記事には本公開記事があります。

The final version of this article is now available: Vol. 72 (2008) , No. 2 p.591

詳細

抄録

This study describes the first isolation of hemorrhagic metalloproteinase HR1b from the venom of Okinawa habu, and its cDNA cloning. The substrate specificity of isolated HR1b definitely differed from that of HR1a, further supporting the presence of a metalloproteinase distinguishable from HR1a in the venom of Okinawa habu. The deduced amino acid sequence of HR1b showed 99.67% identity with HR1b of Amami habu, with only two amino acid residue replacements.

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