Antihypertensive Effects and Endothelial Progenitor Cell Activation by Intake of Chicken Collagen Hydrolysate in Pre- and Mild-Hypertension

Ai SAIGA; Koji IWAI; Toru HAYAKAWA; Yoshihisa TAKAHATA; Fumiki MORIMATSU

doi:10.1271/bbb.80189

This article has now been updated. Please use the final version.

Antihypertensive Effects and Endothelial Progenitor Cell Activation by Intake of Chicken Collagen Hydrolysate in Pre- and Mild-Hypertension

Ai SAIGA, Koji IWAI, Toru HAYAKAWA, Yoshihisa TAKAHATA, Fumiki MORIMATSU

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Keywords: chicken collagen hydrolysate, hypertension, plasma renin activity, endothelial progenitor cell

JOURNAL FREE ACCESS Advance online publication

Article ID: 80189

DOI https://doi.org/10.1271/bbb.80189

The final version of this article is now available: Vol. 73 (2009) , No. 2 p.422

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Abstract

Chicken collagen hydrolysate was given to 15 mildly hypertensive subjects for 4 weeks. Blood pressure was significantly decreased by 11.8 mmHg (P<0.01). A reduction in plasma renin activity was observed in blood test after intake. A colony assay of endothelial progenitor cells in blood samples from non-smokers revealed an approximately 30% increase in the number of colonies.

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