Published: November 23, 2008Received: June 25, 2008Available on J-STAGE: -Accepted: July 23, 2008
Advance online publication: November 07, 2008
Revised: -
Circadian clocks, especially peripheral clocks, can be strongly entrained by daily feedings, but few papers have reported the effects of food components on circadian rhythm. The effects of resveratrol, a natural polyphenol, on circadian clocks of Rat-1 cells were analyzed. A dose of 100 μM resveratrol, which did not show cytotoxicity, regulated the expression of clock genes Per1, Per2, and Bma1l.
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