Involvement of LEM3/ROS3 in the Uptake of Phosphatidylcholine with Short Acyl Chains in Saccharomyces cerevisiae

Yusuke ONO; Ryouichi FUKUDA; Akinori OHTA

doi:10.1271/bbb.80675

This article has now been updated. Please use the final version.

Involvement of LEM3/ROS3 in the Uptake of Phosphatidylcholine with Short Acyl Chains in Saccharomyces cerevisiae

Yusuke ONO, Ryouichi FUKUDA, Akinori OHTA

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Keywords: Saccharomyces cerevisiae, phosphatidylcholine, uptake

JOURNAL FREE ACCESS Advance online publication

Article ID: 80675

DOI https://doi.org/10.1271/bbb.80675

The final version of this article is now available: Vol. 73 (2009) , No. 3 p.750

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Abstract

A Saccharomyces cerevisiae strain deficient in phosphatidylethanolamine methyltransferase that exhibits choline auxotrophy grew in the presence of dioctanoyl phosphatidylcholine (diC8PC). We isolated and characterized mutants defective in growth in the diC8PC-containing medium. Mutations in LEM3/ROS3 impaired growth in that medium, indicating that Lem3p is involved in the utilization of extracellular phosphatidylcholine (PC) with short acyl chains.

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