Prebiotic Effect of Lacto-N-biose I on Bifidobacterial Growth

Masashi KIYOHARA; Asaki TACHIZAWA; Mamoru NISHIMOTO; Motomitsu KITAOKA; Hisashi ASHIDA; Kenji YAMAMOTO

doi:10.1271/bbb.80697

This article has now been updated. Please use the final version.

Prebiotic Effect of Lacto-N-biose I on Bifidobacterial Growth

Masashi KIYOHARA, Asaki TACHIZAWA, Mamoru NISHIMOTO, Motomitsu KITAOKA, Hisashi ASHIDA, Kenji YAMAMOTO

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Keywords: Bifidobacterium, bifidus factor, lacto-N-biose I, milk oligosaccharide, prebiotics

JOURNAL FREE ACCESS Advance online publication

Article ID: 80697

DOI https://doi.org/10.1271/bbb.80697

The final version of this article is now available: Vol. 73 (2009) , No. 5 p.1175

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Abstract

We demonstrated the prebiotic effect of lacto-N-biose I (Galβ1-3GlcNAc) on bifidobacteria in vitro. Lacto-N-biose I, a building unit of the type-I milk oligosaccharides, enhanced the growth of many bifidobacteria, especially Bifidobacterium bifidum, B. breve, and B. longum, which are predominant in the intestines of breast-fed infants. It might be a substantial, natural prebiotic in human colostrums.

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