SK66-his, a Novel Glycine-Rich Peptide Derived from Drosophila with Antibacterial Activity

Zhiguo FENG; Huijuan LIU; Jun LANG; Yanjiao LI; Muya SHU; Zhengwang CHEN

doi:10.1271/bbb.80756

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SK₆₆-his, a Novel Glycine-Rich Peptide Derived from Drosophila with Antibacterial Activity

Zhiguo FENG, Huijuan LIU, Jun LANG, Yanjiao LI, Muya SHU, Zhengwang CHEN

著者情報

キーワード: antibacterial peptides, glycine-rich, expression, purification, Drosophila

ジャーナルフリー早期公開

論文ID: 80756

DOI https://doi.org/10.1271/bbb.80756

この記事には本公開記事があります。

The final version of this article is now available: Vol. 73 (2009) , No. 3 p.769

詳細

抄録

SK₆₆-his, a novel glycine-rich peptide derived from the CG13551 gene of Drosophila, was directly expressed in Escherichia coli with the help of the glucose effect of the lac repressor and efficiently purified in high yield (10.063 mg/l). It showed significant activity against Gram-positive bacteria. We determined a MIC value of 9 μg ml⁻¹ with Bacillus thuringiensis.

責任著者(Corresponding author)

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