Dietary Resistant Starch Reduces Histone Acetylation on the Glucose-Dependent Insulinotropic Polypeptide Gene in the Jejunum

Masaya SHIMADA; Kazuki MOCHIZUKI; Toshinao GODA

doi:10.1271/bbb.90384

この記事には本公開記事があります。本公開記事を参照してください。
引用する場合も本公開記事を引用してください。

Dietary Resistant Starch Reduces Histone Acetylation on the Glucose-Dependent Insulinotropic Polypeptide Gene in the Jejunum

Masaya SHIMADA, Kazuki MOCHIZUKI, Toshinao GODA

著者情報

キーワード: resistant starch, glucose-dependent insulinotropic polypeptide, histone acetylation, chromatin, small intestine

ジャーナルフリー早期公開

論文ID: 90384

DOI https://doi.org/10.1271/bbb.90384

この記事には本公開記事があります。

The final version of this article is now available: Vol. 73 (2009) , No. 12 p.2754

詳細

抄録

We have reported that dietary resistant starch (RS) reduces glucose-dependent insulinotropic polypeptide (GIP) mRNA levels along the jejunoileum in both normal and diabetic rats. In this study, we found that jejunal reduction of the GIP gene by feeding normal rats dietary RS was associated with decreases in histone H3 and H4 acetylation on the promoter/enhancer region of the gene.

責任著者(Corresponding author)

J-STAGEへの登録はこちら（無料）