Reaktion des Äthylenoxyds auf Aminosäure und Eiweissstoffe

Abstract

Ethylene oxide reacted for the first time with amino group of amino acid in alkali side under mild conditions, when magnesium ion was added. In the conditions N-hydroxyethyl-alanine was isolated from the reaction mixture consisting of alanine and ethylene oxide.
One mol of trypsin combined with 10 mols of ethylene oxide at 5°C, pH 8.0 in 12 days, but the change in the activity through combination was not plain.