抄録
The present paper is concerned with the availability of the acyl derivatives of lysine for the growth of young rats in the course of studying the enzymatic resolution of DL-lysine with mold acylase. The enzymatic resolution of DL-lysine to optically-active L and D-isomers was carried out in either of the following two ways, namely, the asymmetric hydrolysis of diacetyl-DL-lysine or that of e-benzoyl-a-acetyl-DL-lysine.
The oral administration of ε-acetyl-L-lysine to rats fed on the lysine-deficient diet supported the growth of young rats at a rate approximately two-thirds of that observed when L-lysine was supplied. ε-Benzoyl-L-lysine proved to be quite ineffective while diacetyl lysine showed a slight but insignificant increase in body weight.
