Studies on the Metabolism of D-Amino Acid in Microorganisms

Part VII. Possible Involvement of Cell Permeability in the Metabolism of L-Glutamic Acid by Aerobacter aerogenes Strain A

Abstract

Several experiments were made in order to clarify the reason why Aerobacter aerogenes strain A can grow well on D-glutamate-K₂HPO₄ medium, while it can not grow on L-glutamate medium at neutral pH value. The permeabilities of L- and D-glutamic acids to the bacterial cell membrane seem to play some important role on this phenomenon judging from several experimental results on growth tests and enzymatic studies.