抄録
1) E. coli was able to produce α-ketoglutarate when the organism was grown aerobically on the media containing various kinds of carbohydrates; carbohydrates tested were lactose, maltose, sucrose, D-glucose, D-fructose, n-galactose, D-mannose, n-mannitol, L-rhamnose, D-xylose, L-arabinose and glycerin.
2) The effects of the pH of the media upon a-ketoglutarate-fermentation were investigated.
3) A striking effect of inorganic phosphate was observed on the production of α-ketogluta-rate.
4) A statically grown cell of E. coli was found to be capable of inducing a-ketoglutarate-fer-mentation.
5) L lactic acid was potent in the produc-tion of α-ketoglutarate.
6) The action of various reagents was in-vestigated and the inhibiting effects on α-keto-glutarate-fermentation were observed with CuSO4, AgNO3, iodoacetate, 2, 4-dinitrophenol, NaN3, 3-sulfanil-amido-6-methoxy pyridazine and arsenite.
7) A small supply of air into a glucose-medium increased the yield of acetate against decreasing α-ketoglutarate.