抄録
In connection with the preceding paper concerning the enhancement of radiation lethal effect by the NaCl treatment, the experimental evidences and the further discussion for the possible mechanism of the enhancement by the post-NaCl treatment are presented.
In order to elucidate the radiation damages of cell constituents and its enhancement by NaCl, the infrared analysis and isotopic experiments were carried out with cells of S. cereoisiae, Z. soya and E. coll.
Consequently, it has been concluded that the possible mechanism may involve the processes of increase in cell permeability by irradiation and of the denaturation of the critical cell constituents by increasing penetration of NaCl and thus the sensitivity of irradiated cells to NaCl may increase. The NaCl sensitive sites are considered not to be restricted to the biological targets for radiation inactivation by the supports of the survival curve analysis based on the target theory and of the isotopic experiment.
