A New Toxic Substance, Teleocidin, Produced by Streptonayces

Part II. Biological Studies of Teleocidin

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Biological activities of a new toxic substance, Teleocidin, produced by a Streptomyces were examined. Among the toxic antibiotics produced by Streptomyces, 9 antibiotics were also tested for their toxicity toward Oryzias latipes, Daphnia magna and Bugula neritina larvae, and Antimycin A was found to show equal or more severe toxicity than Teleocidin.
Teleocidin has shown certain inhibitory actions to Ascaris suilla and Turbatrix aceti and also has severe toxicity and skin irritative effects on mammalians.