抄録
In a rat poisoned with sodium fluoroacetate no accumulation of citrate was found in theliver, while in that of a frog fluoroacetate administration was found to cause a markedincrease of citrate. In this paper, it was shown that even in a rat when it was treated withinsulin before fluoroacetate administration, citrate accumulation could be found in the liver. In the experiments in vitro using slices of a rat liver it was also shown that fluoroacetate couldcause an accumulation of citrate and inhibited the oxidation of malate in the slices of a normalas well as an insulinized liver.
