Studies on the Pentose Isomerases of Lactic Acid Bacteria

Part IV. Effects and Requirement of Metal

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D-Xylose isomerase requires manganese ions for its action, but L-arabinose isomerase hasa less specific on metal requirement. L-Arabinose isomerase is activated by addition of Mn++or Co⁺⁺, less effectively by addition of Zn⁺⁺, Ca⁺⁺, Mg⁺⁺, Sr⁺⁺ or Cd⁺⁺. Moreover, manganeseand potassium ions for D-xylose isomerase, and manganese and cobaltous ions for L-arabinoseisomerase were also shown to have protective effect on respective enzymes against thermal inactivation.