Studies on Utilization of Hydrocarbons by Yeasts

Part II. Diterminal Oxidation of Alkanes by Yeasts

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We found that the yeast Y-3 strain reported in the previous paper¹⁾ has a diterminal oxidation system of hydrocarbon.
This yeast capable of growing in mineral-salts solution with hydrocarbons as sole source of carbon produced a series of dioic acid from n-undecane. These acids are 1, 11-undecane dioic acid, 1, 9-nonane dioic acid (azelaic acid), 1, 7-heptane dioic acid (pimelic acid) and 1, 5-pentane dioic acid (glutaric acid). 1, 10-Decane dioic acid (sebacic acid) was also isolated from n-decane cultures.
Azelaic acid was partially transformed into pimelic acid and glutaric acid by treating it with resting cells of this yeast.
1, 11-Undecane dioic was also transformed into azelaic acid pimelic acid, and glutaric acid by the same treatment as described above.