Studies on Substances Active on the Behavior of Planarian

Part I. Production of trans-3-Methylthioacrylic Acid and 3-Methylthiopropionic Acid by Microorganisms

Abstract

Substances which acted on the behavior of planarian were searched for, and two active components were isolated from culture broth of Streptomyces sp. 340. They were identified as trans-3-methylthioacrylic acid (MTAA) and 3-methylthiopropionic acid (MTPA).
It was found that many Streptomyces and some fungi accumulated MTAA, and many Streptomyces, fungi, bacteria and yeasts accumulated MTPA when the microorganisms were grown in the medium containing methionine.