The Aroma of Cigar Tobacco Part III

Isolation and Synthesis of R-(+)-3-Isopropyl-5-hydroxypentanoic Acid Lactone

Abstract

A minor component of cigar tobacco (+)-3-isopropyl-5-hydroxypentanoic acid lactone (I) was isolated. Synthesis of (+)-I from (+)-limonene established the absolute R-configuration. Stereochemistry of (+)-I is also described.