Effects of Isoleucine, Serine and Sodium Chloride on the Threonine Response of Threonine-sensitive and-requiring Strains of Brevibacterium flavum
1973 年 37 巻 1 号 p. 19-28
詳細
1973 年 37 巻 1 号 p. 19-28
The growth of a threonine-sensitive and-requiring strain of Brevibacterium flavum, QL-5, depended on the threonine concentration in a minimal medium, but it was much slower than that of a simple threonine-requiring mutant, T-36, at a low concentration of threonine. This slow growth of the former was stimulated by the addition of isoleucine plus serine or NaCl.
Since these effectors also stimulated the threonine-sensitivity, isoleucine plus serine at a relatively higher concentration of threonine or an excess amount of NaCl inhibited the growth.
The effect of NaCl was ascribed to that of sodium ions. Lithium chloride as well as BeCl2 showed a similar effect but KCl did not.
Similar promoting effects were also observed with all other threonine-sensitive mutants and a simple threonine-requiring mutant tested in various culture media.
The lysine production by QL-5 was also stimulated by isoleucine plus serine.
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