The Synthesis of (±)-Azetidine-2-carboxylic Acid and 2-Pyrrolidinone Derivatives

Yasuhiro YAMADA; Tomio EMORI; Shinichi KINOSHITA; Hirosuke OKADA

doi:10.1271/bbb1961.37.649

Agricultural and Biological Chemistry

Online ISSN : 1881-1280
Print ISSN : 0002-1369
ISSN-L : 0002-1369

The Synthesis of (±)-Azetidine-2-carboxylic Acid and 2-Pyrrolidinone Derivatives

Yasuhiro YAMADA, Tomio EMORI, Shinichi KINOSHITA, Hirosuke OKADA

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JOURNAL FREE ACCESS

1973 Volume 37 Issue 3 Pages 649-652

DOI https://doi.org/10.1271/bbb1961.37.649

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Abstract

(±)-Azetidine-2-carboxylic acid and 3-substituted-2-pyrrolidinones were synthesized from 2-pyrrolidinone via 3-bromo-2-methoxy-1-pyrroline (IIIa). The bromide (IIIa) was obtained by the bromination of 2-methoxy-1-pyrroline using NBS.

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