Production of Alkaline Protease from Acetic Acid

Abstract

The use of acetic acid as a carbon source in alkaline protease fermentation was examined. Acetic acid was a good carbon source and yielded a great deal of alkaline protease.
Acetic acid has advantages over ordinary carbon sources such as starch and glucose in that it can be supplied to culturing liquid as much as needed to perform the fermentation efficiently, that it has a function to control the pH of culturing liquid at a constant level and that it was obtained at lower price.
The maximum proteolytic activity attained was 1.6×10⁴units/ml (11.4mg-enzyme/ml).