Formation of Phosphatidyl 1-(2-Hydroxyethyl)-2, 3, 5-Trialkyl Pyridinium on Heating Phosphatidyl Ethanolamine with n-Alkanal

Abstract

From the reaction products of phosphatidyl ethanolamine and n-alkanals such as propionaldehyde or n-heptaldehyde at 60°C for 2hr, a series of phosphatidyl 1-(2-hydroxyethyl)2, 3, 5-trialkyl pyridiniums were isolated by silica gel column chromatography and were identified by the elementary analysis, UV, IR and NMR spectral analysis of alkali and acid hydrolyzates of the compounds. The course of formation reaction of pyridinium ring was discussed.