Characterization of 7-[1-(1H)-Tetrazolylacetamido]-desacetoxycephalsporanic Acid Enzymatically Synthesized by Kluyvera citrophila

Mikio SHIMIZU; Taketoshi MASUIKE; Hironori FUJITA; Takao IIDA; Kazuo KIMURA; Takashi NARA

doi:10.1271/bbb1961.39.1745

Agricultural and Biological Chemistry

Online ISSN : 1881-1280
Print ISSN : 0002-1369
ISSN-L : 0002-1369

Characterization of 7-[1-(1H)-Tetrazolylacetamido]-desacetoxycephalsporanic Acid Enzymatically Synthesized by Kluyvera citrophila

Mikio SHIMIZU, Taketoshi MASUIKE, Hironori FUJITA, Takao IIDA, Kazuo KIMURA, Takashi NARA

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JOURNAL FREE ACCESS

1975 Volume 39 Issue 9 Pages 1745-1748

DOI https://doi.org/10.1271/bbb1961.39.1745

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Abstract

Kluyvera citrophila KY7844 enzymatically catalyzed N-acylation of 7-amino-desacetoxycephalosporanic acid with 1-(1H)-tetrazolylacetate methylester to produce 7-[1-(1H)-tetrazolylacetamido]-desacetoxycephalosporanic acid. The product was purified and characterized.

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