Agricultural and Biological Chemistry
Online ISSN : 1881-1280
Print ISSN : 0002-1369
ISSN-L : 0002-1369
Microbial Hydrolysis of Pepsidines
Yoshikazu HASEGAWAYukio NOZUNoriaki KUWANA
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1976 年 40 巻 3 号 p. 451-458

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Microbial hydrolysis of pepsidines was studied by using bacteria. A strain of bacteria which has been isolated from soil and identified as Bacillus pumilus, could release successively N-terminal acetyl moiety and valine from pepsidine C. The residual peptides thus obtained were crystallized and identified as desacyl-pepsidine and desacylvalyl-pepsidine. The correlation between their structures and pepsin inhibitory activities was also studied.
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