Abstract
A bacterium KY 3071 that was found to produce a new aminonucleoside antibiotics, 2'-amino-2'-deoxyguanosine (2 AG), was identified as Enterobacter cloacae KY 3071.
Amount of dipotassium phosphate and ammonium sulfate affected 2 AG production greatly and their concentration must be 0.2 and 15g/liter for the efficient 2 AG production, respectively.
Addition of purine nucleotides promoted 2 AG production, particularly xanthosine-5'-monophosphate was most effective, and purine nucleosides, on the contrary, inhibited the 2 AG production. The maximum amounts of 2 AG were approximately 0.4g/liter after 24 hr of incubation.
