Abstract
The metabolisms of trans-2-octenoic acid (2-OEA) and related compounds were investigated by using one of Mucor species which could reduce sorbic acid to trans-4-hexenol. In a phosphate buffer solution, 3-hydroxyoctanoic acid (3-HOA), monooctyl phosphate (OLP), 1-octanol and 1, 3-octanediol were produced as metabolites of 2-OEA. It was elucidated that the conversion of 2-OEA into 3-HOA was reversible and finally most of the substrate was transformed into OLP via the following pathway: 3-HOA_??_2-OEA→trans-2-octenol→1-octanol→OLP. Similarly, trans-3-octenol and mono-trans-3-octenyl phosphate were produced by the fungus as major metabolites of trans-3-octenoic acid.
