Abstract
SY-1 (I) is an antibiotic produced by Streptoinyces albus ATCC 21838 as a concurrent minor component of salinomycin. The antibiotic was isolated in the form of sodium salt, C42H69O10Na. The structure of I has been established by the NMR and mass spectral evidences as well as by direct comparison of the 18, 19-dihydroSY-1 methyl ester (IV) with 18, 19-dihydro-20-deoxysalinomycin methyl ester (VII). I showed a weak inhibitory activity against gram-positive bacteria and was also effective in the treatment of coccidial infection in chickens.
