Abstract
Twenty amines were examined as catalysts for the phosphorylation of ribonucleoside by MTBO.
Primary n-alkyl and alicyclic amines were good catalysts giving the product in high yields. Branched-chain alkylamines were less effective than straight-chain alkylamines. While secondary amines were less effective than primary amines, the yields of the product were nearly equal to those with primary amines. Cyclic imines, except for morpholine, had high catalytic activities though the yields of the product were low. Tertiary amines were the least effective catalysts.
