Structure Elucidation and Synthesis of Alkaloids Isolated from Fruits of Evodia rutaecarpa

Abstract

Five alkaloids were isolated from ripe fruits of Evodia rutaecarpa HOOK. f. et THOMS. Four of these were found to be indoloquinazoline type alkaloids: rutecarpine (I), evodiamine (II) and two new alkaloids, dihydrorutecarpine (IV) and its 14-formyl derivative (III). The remaining one was a new quinolone alkaloid, 1-methyl-2-nonyl-4(IH)-quinolone (V). The synthesis of II, III and IV was also achieved.