Phase Transfer Catalysis; Nucleophilic Substitution of β-Bromohydrins with Anions in Solid-Liquid System

Abstract

Nucleophilic displacements of β-bromohydrins with azide, phthalimide, acetate and thiocyanate anions were effected by tetramethylethylenediamine (TMEDA), triethylenediamine (TEDA) and 18-crown-6 (CE) in solid-liquid media, to afford the products in various yields and distributions.