抄録
After irradiation with sub-lethal doses of γ-rays, cells of M. radiodurans stop temporarily the incorporation of DNA precursors into acid-insoluble fraction no matter how much the dosage. However, the length of lag period to restore its normal rate of DNA synthesis depends on the dose of irradiation.
In permeable cells prepared after irradiation and reincubation in a growth medium, nonconservative-type DNA synthesis was inhibited while the stimulated level of DNA synthesis remained in the permeable cells prepared from the cells that had been reincubated at 0°C in the presence of EDTA. These results suggest involvement of some regulatory system for DNA synthesis in M. radiodurans that might play an important role in its high radioresistance.
