Synthesis of (S)-(+)-Methyl β, γ-Dihydroxy-α-methylenebutyrate and (S)-(-)-Tulipalin B

Abstract

The synthesis of (S)-(+)-methyl β, γ-dihydroxy-α-methylenebutyrate and (S)-(-)-tulipalin B, antibacterial substances isolated from Spiraea thunliergii Sieb. has been accomplished starting from isopropylidene-D-glyceraldehyde.