Abstract
Radiolysis of some monosaccharides (fructose, glucose and ribose) in air-free condition was markedly enhanced by the addition of formate at concentrations above 20mM, while it was inhibited at concentrations below 20mM. The following compounds were detected in the irradiated sugar solutions containing excess formate (100mM): 1-Deoxy-D-arabinohexulose (1, G=4.4) and 1, 3-dideoxy-D-erythrohexulose (2, G=1.3) from fructose; 2-deoxy-D-ribose (3, G=2.3) and 2-deoxyribitol (4, G=0.6) from ribose; and 2-deoxy-D-glucose (5, G=0.5) and 2-deoxy-D-glucitol (6, G=0.4) from glucose. A mechanism for radiolytic formation of the products was proposed, based on interaction of CO2- formed from formate with sugars.
