抄録
Two bacterial strains which degrade nicotine and nicotine-1'-N-oxide were isolated from tobacco leaves and soils, and their bacteriological characteristics were investigated. One strain was white and the other yellow and both were identified as Arthrobacter globiformis (Conn) Conn and Dimmick. A. globiformis JTS-6 had a marked substrate specificity for nicotine-1'-N-oxide and did not degrade the other N-oxide analogues tested, showing that pyridine and pyrrolidine rings were required for the substrate. Strain JTS-6 degraded natural (S)-nicotine two-times as fast as (R)-nicotine. It degraded all four diastereomers of nicotine-1'-N-oxide, although 1'(R) were degraded faster than 1'(S) without distinction for 2' configuration.