Taxonomy of Producing Organism, and Production, Isolation, Physico-chemical Properties and Biological Activities of Cirratiomycin A and B

Abstract

The new peptide antibiotics have been obtained from the culture filtrate of a streptomycete, strain 248-Sq2, isolated from a soil sample collected at Nagano Prefecture, Japan.
On the basis of taxonomic studies, the producing organisms is designated as Streptomyces cirratus. Two active principles are named cirratiomycin A and B.
These antibiotics exhibit a narrow range of activities against Lactobacillus casei and some strains of Streptococcus and Mycobacterium.