Synthesis and Absolute Configuration of (+)-8-Hydroxyhexadecanoic Acid, an Endogenous Inhibitor for Spore Germination in Lygodium japonicum

Abstract

(S)-(+)-2-Aminodecanoic acid was converted in 9 steps to (+)-8-hydroxyhexadecanoic acid, an endogenous inhibitor for spore germination in Lygodium japonicum, establishing its absolute configuration to be S.