Synthesis of Brassinolide Analogs and Their Plant Growth-promoting Activity

Abstract

Brassinolide analogs such as (22S, 23S)-28-norbrassinolide 8b, a lactam (6-aza-7-keto analog) 12b, a thiolactam (6-aza-7-thiono analog) 14b and an isomer (6-oxa-7-keto isomer) 15b of (22S, 23S)-homobrassinolide were synthesized. Only two of them (8b and 15b) were bioactive.