A screening test was carried out to obtain microbes which produce fruiting-body inducing substances and an inducer was found in the culture broth of an actinomycete, strain TO 447. This strain was identified as Streptomyces albulus from its taxonomical characteristics. The fruiting-body inducing substance produced by this strain was isolated and identified as Cyclooctasulfur by spectroscopic evidence. Cyclooctasulfur induced the fruiting-body formation of Favolus arcularius in a dosage range of 0.01-1000ng/disc.
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