Ganoderiol A and B, New Triterpenoids from the Fungus Ganoderma lucidum (Reishi)

Abstract

Two new lanostane-type triterpenoids, ganoderiol A (1) and ganoderiol B (2) were isolated from the fruiting bodies of Ganoderma lucidum, together with known ganodermanontriol (3) and ganodermatriol (4). The compounds were identified as 5∝-lanosta-7, 9(ll)-dien-3β, 24, 25, 26-tetraol (1), 15a, 26, 27-trihydroxy-5α-lanosta-7, 9(11), 24-trien-3-one (2), 24, 25, 26-trihydroxy-5α-lanosta7, 9(1l)-dien-3-one (3) and 5α-lanosta-7, 9(11), 24-trien-3β, 26, 27-triol (4), respectively.